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Aprea Therapeutics (APRE) said Wednesday that initial data from a phase 1 trial showed that APR-1051
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Generally, when a single insider buys stock, it is usually not a big deal. However, when several insiders are buying...
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Preclinical data demonstrate potent single-agent and combination effects in head and neck squamous cell carcinoma (HNSCC) models, including synergy with anti–PD-1 therapy Initial Phase 1 clinical update shows early disease control in first HPV+ patient treated with APR-1051 DOYLESTOWN, Pa., June 25, 2025 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage biopharmaceutical company developing innovative treatments that exploit specific cancer
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ATRN-119, our ATR inhibitor, exhibits early evidence of single agent, anti-tumor activity and is progressing toward the recommended Phase 2 dose (RP2D) in the ongoing ABOYA-119 clinical trial Three patients in the 550 mg twice daily cohort in the ongoing ABOYA-119 clinical trial demonstrated tumor shrinkage of 7%, 14% and 21% ACESOT-1051, the Phase 1 trial of WEE1 inhibitor APR-1051, continues to advance, with patients now being dosed at 100 mg once daily $19.3 million in cash and cash equivalen
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According to the company, the trial’s open-label data is anticipated in the latter half of this year.
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ACESOT-1051 Trial Expanded to Include HPV+ Head and Neck Squamous Cell Carcinoma (HNSCC) Patients, Targeting Populations Most Likely to Benefit for WEEI InhibitionDOYLESTOWN, Pa., March 31, 2025 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage biopharmaceutical company developing innovative treatments that exploit specific cancer cell vulnerabilities while minimizing damage to healthy cells, today announced that a patient with HPV+ head an
Current Value
$1.651 Year Return
Current Value
$1.651 Year Return
| Name | Correlation | Market Cap | Return % (1 Year) | Div Yield % |
|---|---|---|---|---|
| VIST | -0.01% | $4.60B | +6.03% | 0.00% |
| VTR | -0.01% | $28.41B | +21.44% | 2.95% |
| BR | -0.01% | $27.96B | +19.31% | 1.47% |
| AFYA | 0.01% | $1.59B | +2.33% | 0.00% |
| GSM | -0.02% | $791.29M | -24.82% | 1.26% |
| WM | 0.02% | $89.89B | +6.28% | 1.41% |
| SW | -0.03% | $24.63B | +2.08% | 3.10% |
| PPL | 0.03% | $24.79B | +21.83% | 3.15% |
| EDU | 0.04% | $8.43B | -36.84% | 0.00% |
| DLNG | 0.05% | $131.88M | -7.91% | 4.05% |
| KLAC | -0.05% | $121.81B | +7.94% | 0.74% |
| PAGP | 0.06% | $3.86B | -1.41% | 0.00% |
| LTM | -0.06% | $12.63B | -95.46% | 2.42% |
| MTDR | 0.06% | $6.34B | -16.29% | 2.12% |
| VTLE | -0.07% | $659.45M | -62.97% | 0.00% |
| DVA | 0.07% | $10.76B | +3.34% | 0.00% |
| HES | -0.08% | $44.39B | -3.81% | 1.39% |
| CWEN.A | -0.08% | $3.56B | +34.52% | 5.66% |
| POOL | -0.09% | $11.38B | +0.52% | 1.62% |
| PKX | 0.09% | $16.46B | -19.79% | 2.33% |
| Name | Correlation | Market Cap | Return % (1 Year) | Div Yield % |
|---|---|---|---|---|
| CLFD | 32.26% | $606.07M | +17.01% | 0.00% |
| OKLO | 31.88% | $7.50B | +522.18% | 0.00% |
| EYPT | 28.94% | $664.72M | +12.07% | 0.00% |
| NNOX | 28.35% | $339.85M | -24.50% | 0.00% |
| ACET | 26.60% | $50.78M | -43.67% | 0.00% |
| TLPH | 26.46% | $9.25M | -50.98% | 0.00% |
| AB | 26.17% | $4.57B | +21.69% | 8.09% |
| FOLD | 26.13% | $1.83B | -39.35% | 0.00% |
| BTBT | 26.06% | $745.69M | -19.82% | 0.00% |
| WRAP | 25.80% | $78.39M | -14.84% | 0.00% |
| IRDM | 25.73% | $3.41B | +17.52% | 1.76% |
| OCUL | 25.32% | $1.51B | +41.41% | 0.00% |
| BIP | 24.96% | $15.61B | +17.61% | 4.92% |
| TSM | 24.91% | $1.21T | +28.01% | 1.14% |
| PLRX | 24.64% | $73.66M | -88.66% | 0.00% |
| AUTL | 24.35% | $625.43M | -32.66% | 0.00% |
| MGTX | 24.30% | $556.13M | +72.14% | 0.00% |
| GRVY | 24.30% | $457.59M | -17.70% | 0.00% |
| CMBM | 24.12% | $11.39M | -82.98% | 0.00% |
| VTYX | 24.10% | $143.75M | -9.01% | 0.00% |
| Name | Correlation | Market Cap | Return % (1 Year) | Div Yield % |
|---|---|---|---|---|
| PPC | -15.68% | $10.84B | +33.46% | 0.00% |
| FI | -13.85% | $95.61B | +15.90% | 0.00% |
| MOH | -13.68% | $12.95B | -19.36% | 0.00% |
| CL | -12.97% | $74.88B | -3.64% | 2.19% |
| GIS | -12.55% | $29.20B | -14.66% | 4.47% |
| CNC | -12.05% | $16.81B | -49.40% | 0.00% |
| ARCO | -11.18% | $1.64B | -14.10% | 3.08% |
| STNG | -11.10% | $2.14B | -48.70% | 3.80% |
| PEP | -10.78% | $187.12B | -16.06% | 4.02% |
| VZ | -10.30% | $183.79B | +6.01% | 6.18% |
| BG | -10.15% | $10.94B | -25.60% | 3.39% |
| CAG | -10.12% | $10.09B | -24.85% | 6.62% |
| AEP | -10.03% | $55.16B | +17.93% | 3.54% |
| HSY | -10.03% | $35.88B | -3.63% | 3.10% |
| ELV | -9.64% | $79.13B | -33.96% | 1.88% |
| MKC | -9.58% | $20.55B | +9.57% | 2.30% |
| SHLS | -9.34% | $914.45M | -9.29% | 0.00% |
| EOG | -9.24% | $67.07B | -3.07% | 3.07% |
| POST | -9.16% | $6.21B | +6.74% | 0.00% |
| AWK | -9.15% | $27.36B | +9.65% | 2.21% |
| Name | Correlation | AUM | Expense Ratio |
|---|---|---|---|
| BTAL | -15.67% | $296.22M | 1.43% |
| VIXY | -14.15% | $164.54M | 0.85% |
| DBE | -13.67% | $52.20M | 0.77% |
| SOYB | -13.23% | $26.67M | 0.22% |
| TAIL | -11.90% | $99.63M | 0.59% |
| SGOV | -11.58% | $49.21B | 0.09% |
| UGA | -11.42% | $72.33M | 0.97% |
| USDU | -11.41% | $162.43M | 0.5% |
| PDBC | -11.37% | $4.42B | 0.59% |
| USL | -11.00% | $42.23M | 0.85% |
| OILK | -10.95% | $71.87M | 0.69% |
| BNO | -10.83% | $103.79M | 1% |
| CANE | -10.76% | $10.37M | 0.29% |
| COMT | -10.68% | $604.69M | 0.48% |
| DBC | -10.63% | $1.23B | 0.87% |
| USO | -10.44% | $1.13B | 0.6% |
| DBO | -10.26% | $228.24M | 0.77% |
| CCOR | -10.23% | $51.66M | 1.18% |
| GSG | -9.89% | $959.40M | 0.75% |
| UUP | -8.60% | $201.63M | 0.77% |
| Name | Correlation | AUM | Expense Ratio |
|---|---|---|---|
| NUKZ | 29.64% | $374.23M | 0.85% |
| FFTY | 25.85% | $81.20M | 0.8% |
| IWC | 24.75% | $818.14M | 0.6% |
| SIXG | 24.73% | $628.37M | 0.3% |
| URA | 24.63% | $3.82B | 0.69% |
| ITEQ | 24.55% | $98.58M | 0.75% |
| RDTE | 24.46% | $137.93M | 0.97% |
| SWAN | 24.42% | $252.67M | 0.49% |
| IZRL | 24.27% | $116.38M | 0.49% |
| IWMY | 23.94% | $119.32M | 1.02% |
| ARTY | 23.74% | $1.09B | 0.47% |
| JPIB | 23.52% | $910.86M | 0.5% |
| ARKG | 23.24% | $1.02B | 0.75% |
| PRNT | 23.16% | $76.77M | 0.66% |
| ICVT | 22.91% | $2.53B | 0.2% |
| BLCN | 22.88% | $47.52M | 0.68% |
| IHAK | 22.86% | $951.11M | 0.47% |
| ARKX | 22.75% | $341.31M | 0.75% |
| AOK | 22.74% | $659.95M | 0.15% |
| XSW | 22.70% | $499.42M | 0.35% |
| Name | Correlation | AUM | Expense Ratio |
|---|---|---|---|
| SPIP | -0.07% | $969.51M | 0.12% |
| IXC | -0.07% | $1.73B | 0.41% |
| JMST | 0.10% | $4.06B | 0.18% |
| VDC | 0.24% | $7.60B | 0.09% |
| DBB | 0.26% | $117.01M | 0.77% |
| FSTA | -0.51% | $1.35B | 0.084% |
| VNM | -0.54% | $421.77M | 0.68% |
| KCCA | 0.62% | $109.43M | 0.87% |
| BILS | -0.64% | $3.81B | 0.1356% |
| VDE | -0.65% | $7.00B | 0.09% |
| KRBN | -0.68% | $160.17M | 0.85% |
| SHM | 0.68% | $3.41B | 0.2% |
| XONE | 0.68% | $625.28M | 0.03% |
| CGSM | 0.69% | $709.45M | 0.25% |
| FXN | -0.79% | $277.65M | 0.62% |
| FENY | -0.79% | $1.29B | 0.084% |
| GOVT | 0.79% | $27.54B | 0.05% |
| RSPG | -0.79% | $428.86M | 0.4% |
| PWZ | 0.84% | $759.91M | 0.28% |
| BSMW | 0.86% | $107.45M | 0.18% |
